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Mutant structure of metabolic switch protein in complex with monomeric c-di-GMP reveals a potential mechanism of protein-mediated ligand dimerization

Bacterial second messengers c-di-GMP and (p)ppGpp have broad functional repertoires ranging from growth and cell cycle control to the regulation of biofilm formation and virulence. The recent identification of SmbA, an effector protein from Caulobacter crescentus that is jointly targeted by both sig...

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Detalles Bibliográficos
Autores principales: Dubey, Badri Nath, Shyp, Viktoriya, Fucile, Geoffrey, Sondermann, Holger, Jenal, Urs, Schirmer, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944927/
https://www.ncbi.nlm.nih.gov/pubmed/36810577
http://dx.doi.org/10.1038/s41598-023-29110-0

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