Cargando…

Ubiquitin‑conjugating enzymes as potential biomarkers and therapeutic targets for digestive system cancers (Review)

Digestive system cancers are the leading cause of cancer-related death worldwide due to their high morbidity and mortality rates. The current treatment methods include surgical treatment, chemotherapy, radiotherapy and endoscopic treatment, and the precisely targeted therapy of digestive system canc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lei, Xiangxiang, Hu, Xiaoge, Lu, Qiliang, Fu, Wen, Sun, Wen, Ma, Qiancheng, Huang, Dongsheng, Xu, Qiuran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944987/ https://www.ncbi.nlm.nih.gov/pubmed/36799184 http://dx.doi.org/10.3892/or.2023.8500

Ejemplares similares

UCHL3 promotes hepatocellular carcinoma cell migration by de-ubiquitinating and stabilizing Vimentin
por: Ma, Qiancheng, et al.
Publicado: (2023)

LncRNA ALKBH3‐AS1 enhances ALKBH3 mRNA stability to promote hepatocellular carcinoma cell proliferation and invasion
por: Lu, Qiliang, et al.
Publicado: (2022)

Research Progress of DUB Enzyme in Hepatocellular Carcinoma
por: Zhao, Jie, et al.
Publicado: (2022)

The Emerging Role of RNA N6-Methyladenosine Modification in Pancreatic Cancer
por: Hu, Xiaoge, et al.
Publicado: (2022)

Ubiquitin-Conjugating Enzymes in Cancer
por: Bui, Quyen Thu, et al.
Publicado: (2021)

The Ubiquitin Conjugating Enzyme: An Important Ubiquitin Transfer Platform in Ubiquitin-Proteasome System
por: Liu, Weigang, et al.
Publicado: (2020)

The Molecular Basis of Ubiquitin-Conjugating Enzymes (E2s) as a Potential Target for Cancer Therapy
por: Du, Xiaodi, et al.
Publicado: (2021)

UBE2K regulated by IGF2BP3 promotes cell proliferation and stemness in pancreatic ductal adenocarcinoma
por: Fu, Wen, et al.
Publicado: (2023)

Case Report: Retroperitoneal Sarcoma in Six Operations: Our Experience in Operative Management of Blood Vessels
por: Guo, Jinhui, et al.
Publicado: (2022)

Targeting Ferroptosis by Ubiquitin System Enzymes: A Potential Therapeutic Strategy in Cancer
por: Meng, Yu, et al.
Publicado: (2022)

Conjugation of the Ubiquitin Activating Enzyme UBE1 with the Ubiquitin-Like Modifier FAT10 Targets It for Proteasomal Degradation
por: Bialas, Johanna, et al.
Publicado: (2015)

Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes
por: Xu, Zhen, et al.
Publicado: (2008)

What Was the Set of Ubiquitin and Ubiquitin-Like Conjugating Enzymes in the Eukaryote Common Ancestor?
por: Michelle, Caroline, et al.
Publicado: (2009)

Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins
por: Jones, Donald, et al.
Publicado: (2002)

Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation
por: Howard, Rebecca A, et al.
Publicado: (2007)

Ubiquitin-Conjugating Enzyme 9 Promotes Epithelial Ovarian Cancer Cell Proliferation in Vitro
por: Dong, Mei, et al.
Publicado: (2013)

Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening
por: Morreale, Francesca E., et al.
Publicado: (2017)

Targeting CDC34 E2 ubiquitin conjugating enzyme for lung cancer therapy
por: Zhang, Shizhen, et al.
Publicado: (2020)

Editorial: Ubiquitin-Modifying Enzymes as Drug Targets and Biomarkers in Cancer
por: Bell, Jessica L., et al.
Publicado: (2021)

Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import
por: Plafker, Scott M., et al.
Publicado: (2004)

Immune Evasion and Drug Resistance Mediated by USP22 in Cancer: Novel Targets and Mechanisms
por: Guo, Jinhui, et al.
Publicado: (2022)

Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina
por: Mirza, Saima, et al.
Publicado: (2010)

The UBE2D ubiquitin conjugating enzymes: Potential regulatory hubs in development, disease and evolution
por: Roman-Trufero, Monica, et al.
Publicado: (2022)

Ubiquitin-conjugating enzyme UBE2J1 negatively modulates interferon pathway and promotes RNA virus infection
por: Feng, Tingting, et al.
Publicado: (2018)

Ubiquitin control of S phase: a new role for the ubiquitin conjugating enzyme, UbcH7
por: Whitcomb, Elizabeth A, et al.
Publicado: (2009)

Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes
por: Yan, Wenjing, et al.
Publicado: (2023)

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
por: Bedford, Lynn, et al.
Publicado: (2010)

A Giant Ubiquitin-conjugating Enzyme Related to IAP Apoptosis Inhibitors
por: Hauser, Hans-Peter, et al.
Publicado: (1998)

Role of high ubiquitin-conjugating enzyme E2 expression as a prognostic factor in nasopharyngeal carcinoma
por: Kao, Wan-Chen, et al.
Publicado: (2022)

African Swine Fever Virus Ubiquitin-Conjugating Enzyme Is an Immunomodulator Targeting NF-κB Activation
por: Barrado-Gil, Lucía, et al.
Publicado: (2021)

Pan-Cancer Analyses of the Tumor Microenvironment Reveal That Ubiquitin-Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target
por: Huang, Guang-zhao, et al.
Publicado: (2021)

Ubiquitin-conjugating enzyme 2C (UBE2C) is a poor prognostic biomarker in invasive breast cancer
por: Kariri, Yousif, et al.
Publicado: (2022)

The ubiquitin-activating enzyme, UBA1, as a novel therapeutic target for AML
por: Barghout, Samir H., et al.
Publicado: (2018)

A Systematic Review of Long Noncoding RNAs in Hepatocellular Carcinoma: Molecular Mechanism and Clinical Implications
por: Hu, Xiaoge, et al.
Publicado: (2018)

MEX3C as a potential target for hepatocellular carcinoma drug and immunity: combined therapy with Lenvatinib
por: Guo, Jinhui, et al.
Publicado: (2023)

Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the Toll-Like Receptor 4/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma
por: Gao, Shan, et al.
Publicado: (2020)

CEACAM6 is a prognostic biomarker and potential therapeutic target for gastric carcinoma
por: Ru, Guo-Qing, et al.
Publicado: (2017)

Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability
por: Shukla, Prakash K., et al.
Publicado: (2022)

A conserved asparagine plays a structural role in ubiquitin-conjugating enzymes
por: Berndsen, Christopher E., et al.
Publicado: (2013)

E2 ubiquitin conjugating enzymes regulate the deubiquitinating activity of OTUB1
por: Wiener, Reuven, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_4uuh4ur4bntrpclmehstpag8ju