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NADPH oxidase 4 deficiency attenuates experimental osteoarthritis in mice

OBJECTIVE: Low-grade inflammation plays a pivotal role in osteoarthritis (OA) through exposure to reactive oxygen species (ROS). In chondrocytes, NADPH oxidase 4 (NOX4) is one of the major ROS producers. In this study, we evaluated the role of NOX4 on joint homoeostasis after destabilisation of the...

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Detalles Bibliográficos
Autores principales:	Renaudin, Félix, Oudina, Karim, Gerbaix, Maude, McGilligan Subilia, Manon, Paccaud, Joris, Jaquet, Vincent, Krause, Karl-Heinz, Ferrari, Serge, Laumonier, Thomas, Hannouche, Didier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Osteoarthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945017/ https://www.ncbi.nlm.nih.gov/pubmed/36810185 http://dx.doi.org/10.1136/rmdopen-2022-002856

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