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Double-blind, randomised placebo-controlled clinical trial of metformin as an adjunct to a sleep–wake, activity and metabolically focused behavioural intervention to improve cardiometabolic outcomes and mood symptoms in youth with major mood syndromes: study protocol
INTRODUCTION: Metformin is a medication likely to improve measures of cardiometabolic disturbance in young people with mental illness. Evidence also suggests metformin may improve depressive symptoms. This 52-week double-blind randomised control trial (RCT) aims to investigate the efficacy of metfor...
Autores principales: | Wilson, Chloe, Carpenter, Joanne Sarah, Nichles, Alissa, Zmicerevska, Natalia, Song, Yun Ju Christine, McHugh, Catherine, Hamilton, Blake, Hockey, Samuel, Crouse, Jacob, Koethe, Dagmar, Scott, Elizabeth M, Hickie, Ian B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945047/ https://www.ncbi.nlm.nih.gov/pubmed/36810174 http://dx.doi.org/10.1136/bmjopen-2022-064682 |
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