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Grouper cGAS is a negative regulator of STING-mediated interferon response

Cyclic GMP-AMP synthase (cGAS) is one of the classical pattern recognition receptors that recognizes mainly intracytoplasmic DNA. cGAS induces type I IFN responses to the cGAS-STING signaling pathway. To investigate the roles of cGAS-STING signaling pathway in grouper, a cGAS homolog (named EccGAS)...

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Detalles Bibliográficos
Autores principales:	Zhang, Luhao, Zhang, Xin, Liao, Jiaming, Xu, Linting, Kang, Shaozhu, Chen, Hong, Sun, Mengshi, Wu, Siting, Xu, Zhuqing, Wei, Shina, Qin, Qiwei, Wei, Jingguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945316/ https://www.ncbi.nlm.nih.gov/pubmed/36845102 http://dx.doi.org/10.3389/fimmu.2023.1092824

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