Indoleamine 2,3 dioxygenase 1 immobilization on magnetic nanoparticles for screening inhibitors from coffee

In this study, a ligand fishing method was developed to screen potential indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors from coffee extracts by immobilization of IDO1 enzyme on amino-modified magnetic nanoparticles combined with UHPLC-Q-TOF-MS/MS analysis. Parameters including enzyme concentration,...

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Detalles Bibliográficos
Autores principales: Liu, Zhuoting, Ping, Yunfang, Zhang, Lumei, Zhang, Jingran, Van Schepdael, Ann, Wang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945408/
https://www.ncbi.nlm.nih.gov/pubmed/36845477
http://dx.doi.org/10.1016/j.fochx.2023.100591

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