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Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE
Resident-tissue macrophages (RTMs) arise from embryonic precursors(1,2), yet the developmental signals that shape their longevity remain largely unknown. Here we demonstrate in mice genetically deficient in 12-lipoxygenase and 15-lipoxygenase (Alox15(−/−) mice) that neonatal neutrophil-derived 12-HE...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945843/ https://www.ncbi.nlm.nih.gov/pubmed/36599368 http://dx.doi.org/10.1038/s41586-022-05660-7 |