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Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE

Resident-tissue macrophages (RTMs) arise from embryonic precursors(1,2), yet the developmental signals that shape their longevity remain largely unknown. Here we demonstrate in mice genetically deficient in 12-lipoxygenase and 15-lipoxygenase (Alox15(−/−) mice) that neonatal neutrophil-derived 12-HE...

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Detalles Bibliográficos
Autores principales:	Pernet, Erwan, Sun, Sarah, Sarden, Nicole, Gona, Saideep, Nguyen, Angela, Khan, Nargis, Mawhinney, Martin, Tran, Kim A., Chronopoulos, Julia, Amberkar, Dnyandeo, Sadeghi, Mina, Grant, Alexandre, Wali, Shradha, Prevel, Renaud, Ding, Jun, Martin, James G., Thanabalasuriar, Ajitha, Yipp, Bryan G., Barreiro, Luis B., Divangahi, Maziar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945843/ https://www.ncbi.nlm.nih.gov/pubmed/36599368 http://dx.doi.org/10.1038/s41586-022-05660-7

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