The fidelity of transcription in human cells

To determine the error rate of transcription in human cells, we analyzed the transcriptome of H1 human embryonic stem cells with a circle-sequencing approach that allows for high-fidelity sequencing of the transcriptome. These experiments identified approximately 100,000 errors distributed over ever...

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Detalles Bibliográficos
Autores principales: Chung, Claire, Verheijen, Bert M., Zhang, Xinmin, Huang, Biao, Coakley, Aeowynn, McGann, Eric, Wade, Emily, Dinep-Schneider, Olivia, LaGosh, Jessica, Anagnostou, Maria-Eleni, Simpson, Stephen, Thomas, Kelly, Ernst, Mimi, Rattray, Allison, Lynch, Michael, Kashlev, Mikhail, Benayoun, Berenice A., Li, Zhongwei, Strathern, Jeffrey, Gout, Jean-Francois, Vermulst, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945944/
https://www.ncbi.nlm.nih.gov/pubmed/36696440
http://dx.doi.org/10.1073/pnas.2210038120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945944/
https://www.ncbi.nlm.nih.gov/pubmed/36696440
http://dx.doi.org/10.1073/pnas.2210038120

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