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The fidelity of transcription in human cells

To determine the error rate of transcription in human cells, we analyzed the transcriptome of H1 human embryonic stem cells with a circle-sequencing approach that allows for high-fidelity sequencing of the transcriptome. These experiments identified approximately 100,000 errors distributed over ever...

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Detalles Bibliográficos
Autores principales:	Chung, Claire, Verheijen, Bert M., Zhang, Xinmin, Huang, Biao, Coakley, Aeowynn, McGann, Eric, Wade, Emily, Dinep-Schneider, Olivia, LaGosh, Jessica, Anagnostou, Maria-Eleni, Simpson, Stephen, Thomas, Kelly, Ernst, Mimi, Rattray, Allison, Lynch, Michael, Kashlev, Mikhail, Benayoun, Berenice A., Li, Zhongwei, Strathern, Jeffrey, Gout, Jean-Francois, Vermulst, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945944/ https://www.ncbi.nlm.nih.gov/pubmed/36696440 http://dx.doi.org/10.1073/pnas.2210038120

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