Loss of the E3 ubiquitin ligases UBR-5 or HECD-1 restores Caenorhabditis elegans development in the absence of SWI/SNF function

SWItch/sucrose non-fermenting (SWI/SNF) complexes are a family of chromatin remodelers that are conserved across eukaryotes. Mutations in subunits of SWI/SNF cause a multitude of different developmental disorders in humans, most of which have no current treatment options. Here, we identify an alanin...

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Detalles Bibliográficos
Autores principales: Lampersberger, Lisa, Conte, Francesca, Ghosh, Subhanita, Xiao, Yutong, Price, Jonathan, Jordan, David, Matus, David Q., Sarkies, Peter, Beli, Petra, Miska, Eric A., Burton, Nicholas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945973/
https://www.ncbi.nlm.nih.gov/pubmed/36689659
http://dx.doi.org/10.1073/pnas.2217992120

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