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Topical Decorin Reduces Corneal Inflammation and Imparts Neuroprotection in a Mouse Model of Benzalkonium Chloride-induced Corneal Neuropathy

PURPOSE: We evaluated the neuroprotective and immunomodulatory effects of topical decorin in a murine model of benzalkonium chloride (BAK)-induced corneal neuropathy. METHODS: Topical BAK (0.1%) was administered daily to both eyes of female C57BL/6J mice (n = 14) for 7 days. One group of mice receiv...

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Detalles Bibliográficos
Autores principales: Wu, Mengliang, Downie, Laura E., Hill, Lisa J., Chinnery, Holly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946044/
https://www.ncbi.nlm.nih.gov/pubmed/36809303
http://dx.doi.org/10.1167/iovs.64.2.20