Cargando…

Topical Decorin Reduces Corneal Inflammation and Imparts Neuroprotection in a Mouse Model of Benzalkonium Chloride-induced Corneal Neuropathy

PURPOSE: We evaluated the neuroprotective and immunomodulatory effects of topical decorin in a murine model of benzalkonium chloride (BAK)-induced corneal neuropathy. METHODS: Topical BAK (0.1%) was administered daily to both eyes of female C57BL/6J mice (n = 14) for 7 days. One group of mice receiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Mengliang, Downie, Laura E., Hill, Lisa J., Chinnery, Holly R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Immunology and Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946044/ https://www.ncbi.nlm.nih.gov/pubmed/36809303 http://dx.doi.org/10.1167/iovs.64.2.20

Ejemplares similares

The effect of topical decorin on temporal changes to corneal immune cells after epithelial abrasion
por: Wu, Mengliang, et al.
Publicado: (2022)

The neuroregenerative effects of topical decorin on the injured mouse cornea
por: Wu, Mengliang, et al.
Publicado: (2020)

Corneal Alternations Induced by Topical Application of Benzalkonium Chloride in Rabbit
por: Chen, Wensheng, et al.
Publicado: (2011)

Topographical Distribution and Phenotype of Resident Meibomian Gland Orifice Immune Cells (MOICs) in Mice and the Effects of Topical Benzalkonium Chloride (BAK)
por: Wu, Ching Yi, et al.
Publicado: (2022)

Effects of topical flurbiprofen sodium, diclofenac sodium, ketorolac tromethamine and benzalkonium chloride on corneal sensitivity in normal dogs
por: Cantarella, Raquel de Araújo, et al.
Publicado: (2017)

Benzalkonium Chloride Suppresses Rabbit Corneal Endothelium Intercellular Gap Junction Communication
por: Zhang, Zhenhao, et al.
Publicado: (2014)

Toxicity of antiglaucoma drugs with and without benzalkonium chloride to cultured human corneal endothelial cells
por: Ayaki, Masahiko, et al.
Publicado: (2010)

Defining an Optimal Sample Size for Corneal Epithelial Immune Cell Analysis Using in vivo Confocal Microscopy Images
por: Zhang, Xin Yuan, et al.
Publicado: (2022)

Localization and Expression of Zonula Occludins-1 in the Rabbit Corneal Epithelium following Exposure to Benzalkonium Chloride
por: Chen, Wensheng, et al.
Publicado: (2012)

A mouse dry eye model induced by topical administration of benzalkonium chloride
por: Lin, Zhirong, et al.
Publicado: (2011)

Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy
por: Jiao, Haihan, et al.
Publicado: (2020)

Genoprotective effect of hyaluronic acid against benzalkonium chloride-induced DNA damage in human corneal epithelial cells
por: Wu, Han, et al.
Publicado: (2011)

Nasal Mucosal Dysplasia Induced by Topical Corticosteroids with Benzalkonium Chloride
por: Tamer, Funda, et al.
Publicado: (2018)

Sustained release of decorin to the surface of the eye enables scarless corneal regeneration
por: Hill, Lisa J., et al.
Publicado: (2018)

Aspergilli Response to Benzalkonium Chloride and Novel-Synthesized Fullerenol/Benzalkonium Chloride Nanocomposite
por: Unković, Nikola, et al.
Publicado: (2015)

Evaluation of the cytotoxic effects of ophthalmic solutions containing benzalkonium chloride on corneal epithelium using an organotypic 3-D model
por: Khoh-Reiter, Su, et al.
Publicado: (2009)

Benzalkonium chloride-induced myofibroblastic transdifferentiation of Tenon’s capsule fibroblasts is inhibited by coculture with corneal epithelial cells or by interleukin-10
por: Yamashiro, Chiemi, et al.
Publicado: (2021)

Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride
por: Musial, Gwen, et al.
Publicado: (2022)

Altered Corneal Epithelial Dendritic Cell Morphology and Phenotype Following Acute Exposure to Hyperosmolar Saline
por: Senthil, Kirthana, et al.
Publicado: (2021)

Optical Coherence Tomography Reveals Changes to Corneal Reflectivity and Thickness in Individuals with Tear Hyperosmolarity
por: Deinema, Laura Adelaide, et al.
Publicado: (2017)

Corneal Epithelial “Neuromas”: A Case of Mistaken Identity?
por: Stepp, Mary Ann, et al.
Publicado: (2020)

Diabetic Corneal Neuropathy
por: Mansoor, Hassan, et al.
Publicado: (2020)

Conjunctival and corneal reactions in rabbits following short- and repeated exposure to preservative-free tafluprost, commercially available latanoprost and 0.02% benzalkonium chloride
por: Liang, H, et al.
Publicado: (2008)

Optimization of a Rabbit Dry Eye Model Induced by Topical Instillation of Benzalkonium Chloride
por: Carpena-Torres, Carlos, et al.
Publicado: (2020)

Role of Decorin Core Protein in Collagen Organisation in Congenital Stromal Corneal Dystrophy (CSCD)
por: Kamma-Lorger, Christina S., et al.
Publicado: (2016)

Efficacy and tolerability of benzalkonium chloride-free travoprost in glaucoma patients switched from benzalkonium chloride-preserved latanoprost or bimatoprost
por: García-Feijoo, Julian, et al.
Publicado: (2016)

Effects of Vitamin A on Expressions of Apoptosis Genes Bax and Bcl-2 in Epithelial Cells of Corneal Tissues Induced by Benzalkonium Chloride in Mice with Dry Eye
por: Zhang, Weihua, et al.
Publicado: (2019)

Controversy: Is Benzalkonium Chloride Necessary in Antiglaucoma Drops?
por: Louati, Y, et al.
Publicado: (2012)

Allergic contact dermatitis to dorzolamide and benzalkonium chloride
por: Orsini, Diego, et al.
Publicado: (2018)

Ocular benzalkonium chloride exposure: problems and solutions
por: Goldstein, Michael H., et al.
Publicado: (2021)

Impact of benzalkonium chloride, benzethonium chloride and chloroxylenol on bacterial antimicrobial resistance
por: Maillard, Jean‐Yves
Publicado: (2022)

Research on the Stability of a Rabbit Dry Eye Model Induced by Topical Application of the Preservative Benzalkonium Chloride
por: Li, Chaoyang, et al.
Publicado: (2012)

Morphometric Changes to Corneal Dendritic Cells in Individuals With Mild Cognitive Impairment
por: Dehghani, Cirous, et al.
Publicado: (2020)

Ocular Toxicity of Benzalkonium Chloride Homologs Compared with Their Mixtures
por: Okahara, Akihiko, et al.
Publicado: (2013)

Intrinsic Resistance of Burkholderia cepacia Complex to Benzalkonium Chloride
por: Ahn, Youngbeom, et al.
Publicado: (2016)

Is it time for a moratorium on the use of benzalkonium chloride in eyedrops?
por: D'andrea, Luca, et al.
Publicado: (2022)

Suppression of NLRP3/Caspase-1/GSDMD Mediated Corneal Epithelium Pyroptosis Using Melatonin-Loaded Liposomes to Inhibit Benzalkonium Chloride-Induced Dry Eye Disease
por: Lou, Qi, et al.
Publicado: (2023)

Changes in Ocular Surface Characteristics after Switching from Benzalkonium Chloride-Preserved Latanoprost to Preservative-Free Tafluprost or Benzalkonium Chloride-Preserved Tafluprost
por: Tokuda, Naoto, et al.
Publicado: (2017)

Targeted Decorin Gene Therapy Delivered with Adeno-Associated Virus Effectively Retards Corneal Neovascularization In Vivo
por: Mohan, Rajiv R., et al.
Publicado: (2011)

Diabetic corneal neuropathy: clinical perspectives
por: Bikbova, Guzel, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pr4fh0hod2jbicidrtl8bhdt76