A novel plant‐made monoclonal antibody enhances the synergetic potency of an antibody cocktail against the SARS‐CoV‐2 Omicron variant

This study describes a novel, neutralizing monoclonal antibody (mAb), 11D7, discovered by mouse immunization and hybridoma generation, against the parental Wuhan‐Hu‐1 RBD of SARS‐CoV‐2. We further developed this mAb into a chimeric human IgG and recombinantly expressed it in plants to produce a mAb...

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Detalles Bibliográficos
Autores principales: Jugler, Collin, Sun, Haiyan, Nguyen, Katherine, Palt, Roman, Felder, Mitchell, Steinkellner, Herta, Chen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946148/
https://www.ncbi.nlm.nih.gov/pubmed/36403203
http://dx.doi.org/10.1111/pbi.13970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946148/
https://www.ncbi.nlm.nih.gov/pubmed/36403203
http://dx.doi.org/10.1111/pbi.13970

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