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Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making

There has been debate about whether addition of an irrelevant distractor option to an otherwise binary decision influences which of the two choices is taken. We show that disparate views on this question are reconciled if distractors exert two opposing but not mutually exclusive effects. Each effect...

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Autores principales: Kohl, Carmen, Wong, Michelle XM, Wong, Jing Jun, Rushworth, Matthew FS, Chau, Bolton KH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946441/
https://www.ncbi.nlm.nih.gov/pubmed/36811348
http://dx.doi.org/10.7554/eLife.75007
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author Kohl, Carmen
Wong, Michelle XM
Wong, Jing Jun
Rushworth, Matthew FS
Chau, Bolton KH
author_facet Kohl, Carmen
Wong, Michelle XM
Wong, Jing Jun
Rushworth, Matthew FS
Chau, Bolton KH
author_sort Kohl, Carmen
collection PubMed
description There has been debate about whether addition of an irrelevant distractor option to an otherwise binary decision influences which of the two choices is taken. We show that disparate views on this question are reconciled if distractors exert two opposing but not mutually exclusive effects. Each effect predominates in a different part of decision space: (1) a positive distractor effect predicts high-value distractors improve decision-making; (2) a negative distractor effect, of the type associated with divisive normalisation models, entails decreased accuracy with increased distractor values. Here, we demonstrate both distractor effects coexist in human decision making but in different parts of a decision space defined by the choice values. We show disruption of the medial intraparietal area (MIP) by transcranial magnetic stimulation (TMS) increases positive distractor effects at the expense of negative distractor effects. Furthermore, individuals with larger MIP volumes are also less susceptible to the disruption induced by TMS. These findings also demonstrate a causal link between MIP and the impact of distractors on decision-making via divisive normalisation.
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spelling pubmed-99464412023-02-23 Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making Kohl, Carmen Wong, Michelle XM Wong, Jing Jun Rushworth, Matthew FS Chau, Bolton KH eLife Neuroscience There has been debate about whether addition of an irrelevant distractor option to an otherwise binary decision influences which of the two choices is taken. We show that disparate views on this question are reconciled if distractors exert two opposing but not mutually exclusive effects. Each effect predominates in a different part of decision space: (1) a positive distractor effect predicts high-value distractors improve decision-making; (2) a negative distractor effect, of the type associated with divisive normalisation models, entails decreased accuracy with increased distractor values. Here, we demonstrate both distractor effects coexist in human decision making but in different parts of a decision space defined by the choice values. We show disruption of the medial intraparietal area (MIP) by transcranial magnetic stimulation (TMS) increases positive distractor effects at the expense of negative distractor effects. Furthermore, individuals with larger MIP volumes are also less susceptible to the disruption induced by TMS. These findings also demonstrate a causal link between MIP and the impact of distractors on decision-making via divisive normalisation. eLife Sciences Publications, Ltd 2023-02-22 /pmc/articles/PMC9946441/ /pubmed/36811348 http://dx.doi.org/10.7554/eLife.75007 Text en © 2023, Kohl et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Kohl, Carmen
Wong, Michelle XM
Wong, Jing Jun
Rushworth, Matthew FS
Chau, Bolton KH
Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making
title Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making
title_full Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making
title_fullStr Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making
title_full_unstemmed Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making
title_short Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making
title_sort intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946441/
https://www.ncbi.nlm.nih.gov/pubmed/36811348
http://dx.doi.org/10.7554/eLife.75007
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