Proliferative exhausted CD8(+) T cells exacerbate long-lasting anti-tumor effects in human papillomavirus-positive head and neck squamous cell carcinoma

The survival prognosis of human papillomavirus (HPV)-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) is largely different, and little is known about the anti-tumor mechanism of tumor-infiltrated exhausted CD8(+) T cells (Tex) in HNSCC. We performed cell-level multi-omics sequ...

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Detalles Bibliográficos
Autores principales: Cheng, Danni, Qiu, Ke, Rao, Yufang, Mao, Minzi, Li, Li, Wang, Yan, Song, Yao, Chen, Junren, Yi, Xiaowei, Shao, Xiuli, Huang, Shao Hui, Zhang, Yi, Chen, Xuemei, Wu, Sisi, Yu, Shuaishuai, Liu, Jun, Wang, Haiyang, Peng, Xingchen, Li, Daibo, Yang, Lin, Chen, Li, Ying, Zhiye, Zheng, Yongbo, Zheng, Meijun, Ying, Binwu, Zeng, Xiaoxi, Zhang, Wei, Xu, Wei, Liu, Geoffrey, Chen, Fei, Yu, Haopeng, Zhao, Yu, Ren, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946444/
https://www.ncbi.nlm.nih.gov/pubmed/36811599
http://dx.doi.org/10.7554/eLife.82705

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