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Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme

To inhibit the growth of bacteria, the DA-PPI nanozyme with enhanced peroxidase-like activity was synthesized. The DA-PPI nanozyme was obtained by depositing high-affinity element iridium (Ir) on the surface of Pd-Pt dendritic structures. The morphology and composition of DA-PPI nanozyme were charac...

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Autores principales: Song, Jingfang, He, Jian, Yang, Lin, Wang, Weiguo, Bai, Qinqin, Feng, Wei, Li, Ranhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946763/
https://www.ncbi.nlm.nih.gov/pubmed/36846581
http://dx.doi.org/10.1155/2023/1689455
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author Song, Jingfang
He, Jian
Yang, Lin
Wang, Weiguo
Bai, Qinqin
Feng, Wei
Li, Ranhui
author_facet Song, Jingfang
He, Jian
Yang, Lin
Wang, Weiguo
Bai, Qinqin
Feng, Wei
Li, Ranhui
author_sort Song, Jingfang
collection PubMed
description To inhibit the growth of bacteria, the DA-PPI nanozyme with enhanced peroxidase-like activity was synthesized. The DA-PPI nanozyme was obtained by depositing high-affinity element iridium (Ir) on the surface of Pd-Pt dendritic structures. The morphology and composition of DA-PPI nanozyme were characterized using SEM, TEM, and XPS. The kinetic results showed that the DA-PPI nanozyme possessed a higher peroxidase-like activity than that of Pd-Pt dendritic structures. The PL, ESR, and DFT were employed to explain the high peroxidase activity. As a proof of concept, the DA-PPI nanozyme could effectively inhibit E. coli (G(−)) and S. aureus (G(+)) due to its high peroxidase-like activity. The study provides a new idea for the design of high active nanozymes and their application in the field of antibacterial.
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spelling pubmed-99467632023-02-23 Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme Song, Jingfang He, Jian Yang, Lin Wang, Weiguo Bai, Qinqin Feng, Wei Li, Ranhui Bioinorg Chem Appl Research Article To inhibit the growth of bacteria, the DA-PPI nanozyme with enhanced peroxidase-like activity was synthesized. The DA-PPI nanozyme was obtained by depositing high-affinity element iridium (Ir) on the surface of Pd-Pt dendritic structures. The morphology and composition of DA-PPI nanozyme were characterized using SEM, TEM, and XPS. The kinetic results showed that the DA-PPI nanozyme possessed a higher peroxidase-like activity than that of Pd-Pt dendritic structures. The PL, ESR, and DFT were employed to explain the high peroxidase activity. As a proof of concept, the DA-PPI nanozyme could effectively inhibit E. coli (G(−)) and S. aureus (G(+)) due to its high peroxidase-like activity. The study provides a new idea for the design of high active nanozymes and their application in the field of antibacterial. Hindawi 2023-02-15 /pmc/articles/PMC9946763/ /pubmed/36846581 http://dx.doi.org/10.1155/2023/1689455 Text en Copyright © 2023 Jingfang Song et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Song, Jingfang
He, Jian
Yang, Lin
Wang, Weiguo
Bai, Qinqin
Feng, Wei
Li, Ranhui
Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme
title Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme
title_full Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme
title_fullStr Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme
title_full_unstemmed Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme
title_short Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme
title_sort enhanced peroxidase-like and antibacterial activity of ir-coatedpd-pt nanodendrites as nanozyme
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946763/
https://www.ncbi.nlm.nih.gov/pubmed/36846581
http://dx.doi.org/10.1155/2023/1689455
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