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Lactate secreted via MCT4 from bone-colonizing breast cancer excites sensory neurons via GPR81

Breast cancer (BC) bone metastasis causes bone pain (BP), which detrimentally damages the quality of life and outcome of patients with BC. However, the mechanism of BC-BP is poorly understood, and effective treatments are limited. The present study demonstrated a novel mechanism of BC-BP using a mou...

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Detalles Bibliográficos
Autores principales:	Okui, Tatsuo, Hiasa, Masahiro, Hasegawa, Kazuaki, Nakamura, Tomoya, Ono, Kisho, Ibaragi, Soichiro, Kanno, Takahiro, Sasaki, Akira, Yoneda, Toshiyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946803/ https://www.ncbi.nlm.nih.gov/pubmed/36799150 http://dx.doi.org/10.3892/ijo.2023.5487

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