High-throughput screening identification of a small-molecule compound that induces ferroptosis and attenuates the invasion and migration of hepatocellular carcinoma cells by targeting the STAT3/GPX4 axis

Hepatocellular carcinoma (HCC) is a lethal malignancy. Although considerable efforts have been made in recent years regarding treatments, effective therapeutic drugs for HCC remain insufficient. In the present study, polyphyllin VI was identified as a potential therapeutic drug for HCC by screening...

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Detalles Bibliográficos
Autores principales: Huang, Qi, Li, Jing, Ma, Mengqing, Lv, Minling, Hu, Rui, Sun, Jialing, Zhong, Xin, Sun, Xinfeng, Feng, Wenxing, Ma, Wenfeng, Zhang, Wei, Zhan, Bolin, Han, Zhiyi, Zhou, Xiaozhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946807/
https://www.ncbi.nlm.nih.gov/pubmed/36825585
http://dx.doi.org/10.3892/ijo.2023.5490

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