Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis

Cancers arise through the accumulation of genetic and epigenetic alterations that enable cells to evade telomere-based proliferative barriers and achieve immortality. One such barrier is replicative crisis—an autophagy-dependent program that eliminates checkpoint-deficient cells with unstable telome...

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Detalles Bibliográficos
Autores principales: Nassour, Joe, Aguiar, Lucia Gutierrez, Correia, Adriana, Schmidt, Tobias T., Mainz, Laura, Przetocka, Sara, Haggblom, Candy, Tadepalle, Nimesha, Williams, April, Shokhirev, Maxim N., Akincilar, Semih C., Tergaonkar, Vinay, Shadel, Gerald S., Karlseder, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946831/
https://www.ncbi.nlm.nih.gov/pubmed/36755096
http://dx.doi.org/10.1038/s41586-023-05710-8

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