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Reconstitution of human pyroptotic cell death in Saccharomyces cerevisiae

Pyroptosis is a lytic form of programmed cell death induced by the activation of gasdermins. The precise mechanism of gasdermin activation by upstream proteases remains incompletely understood. Here, we reconstituted human pyroptotic cell death in yeast by inducible expression of caspases and gasder...

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Detalles Bibliográficos
Autores principales:	Ji, Yanhao, Hawkins, Christine J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946934/ https://www.ncbi.nlm.nih.gov/pubmed/36813876 http://dx.doi.org/10.1038/s41598-023-29464-5

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