Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling

Lymphatic malformation (LM) is a vascular anomaly originating from lymphatic endothelial cells (ECs). While it mostly remains a benign disease, a fraction of LM patients progresses to malignant lymphangiosarcoma (LAS). However, very little is known about underlying mechanisms regulating LM malignant...

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Detalles Bibliográficos
Autores principales: Yang, Fuchun, Kalantari, Shiva, Ruan, Banzhan, Sun, Shaogang, Bian, Zhaoqun, Guan, Jun-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946935/
https://www.ncbi.nlm.nih.gov/pubmed/36813768
http://dx.doi.org/10.1038/s41467-023-36562-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946935/
https://www.ncbi.nlm.nih.gov/pubmed/36813768
http://dx.doi.org/10.1038/s41467-023-36562-5

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