Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics

Functional characterization of the cancer clones can shed light on the evolutionary mechanisms driving cancer’s proliferation and relapse mechanisms. Single-cell RNA sequencing data provide grounds for understanding the functional state of cancer as a whole; however, much research remains to identif...

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Detalles Bibliográficos
Autores principales: Jun, Seong-Hwan, Toosi, Hosein, Mold, Jeff, Engblom, Camilla, Chen, Xinsong, O’Flanagan, Ciara, Hagemann-Jensen, Michael, Sandberg, Rickard, Aparicio, Samuel, Hartman, Johan, Roth, Andrew, Lagergren, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946941/
https://www.ncbi.nlm.nih.gov/pubmed/36813776
http://dx.doi.org/10.1038/s41467-023-36202-y

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