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Delivery of microRNA-302a-3p by APTES modified hydroxyapatite nanoparticles to promote osteogenic differentiation in vitro

OBJECTIVE: To demonstrate the miRNA delivery by hydroxyapatite nanoparticles modified with APTES (HA-NPs-APTES) and promote osteogenic gene expression. MATERIALS AND METHODS: Osteosarcoma cells (HOS, MG-63) and primary human mandibular osteoblasts (HmOBs) were co-cultured with HA-NPs-APTES conjugate...

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Detalles Bibliográficos
Autores principales: Limlawan, Pirawish, Marger, Laurine, Durual, Stéphane, Vacharaksa, Anjalee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947005/
https://www.ncbi.nlm.nih.gov/pubmed/36813762
http://dx.doi.org/10.1038/s41405-023-00135-x