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Single cell profiling of γδ hepatosplenic T-cell lymphoma unravels tumor cell heterogeneity associated with disease progression

PURPOSE: Hepatosplenic T-cell lymphoma (HSTCL), mostly derived from γδ T cells, is a rare but very aggressive lymphoma with poor outcomes. In this study, we generated the first single cell landscape for this rare disease and characterized the molecular pathogenesis underlying the disease progression...

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Detalles Bibliográficos
Autores principales: Song, Wei, Zhang, Haixi, Yang, Fan, Nakahira, Kiichi, Wang, Cheng, Shi, Keqian, Zhang, Ruoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947078/
https://www.ncbi.nlm.nih.gov/pubmed/36417130
http://dx.doi.org/10.1007/s13402-022-00745-x