Hydrogen sulfide as an anti-calcification stratagem in human aortic valve: Altered biogenesis and mitochondrial metabolism of H(2)S lead to H(2)S deficiency in calcific aortic valve disease

Hydrogen sulfide (H(2)S) was previously revealed to inhibit osteoblastic differentiation of valvular interstitial cells (VICs), a pathological feature in calcific aortic valve disease (CAVD). This study aimed to explore the metabolic control of H(2)S levels in human aortic valves. Lower levels of bi...

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Detalles Bibliográficos
Autores principales: Combi, Zsolt, Potor, László, Nagy, Péter, Sikura, Katalin Éva, Ditrói, Tamás, Jurányi, Eszter Petra, Galambos, Klaudia, Szerafin, Tamás, Gergely, Péter, Whiteman, Matthew, Torregrossa, Roberta, Ding, Yuchao, Beke, Lívia, Hendrik, Zoltán, Méhes, Gábor, Balla, György, Balla, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles from the Special Issue on Recent advances in sulfur biology and chemistry, Edited by: Dr. Peter Nagy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947110/
https://www.ncbi.nlm.nih.gov/pubmed/36780769
http://dx.doi.org/10.1016/j.redox.2023.102629

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