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Nucleolin recognizing silica nanoparticles inhibit cell proliferation by activating the Bax/Bcl-2/caspase-3 signalling pathway to induce apoptosis in liver cancer

Multifunctional nanocarrier platforms have shown great potential for the diagnosis and treatment of liver cancer. Here, a novel nucleolin-responsive nanoparticle platform was constructed for the concurrent detection of nucleolin and treatment of liver cancer. The incorporation of AS1411 aptamer, ica...

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Detalles Bibliográficos
Autores principales: Xiang, Liangliang, Li, Yun, Gu, Xinyu, Li, Shujie, Li, Junwei, Li, Jinlong, Yi, Yongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947157/
https://www.ncbi.nlm.nih.gov/pubmed/36843953
http://dx.doi.org/10.3389/fphar.2023.1117052