Uncovering the complex genetic architecture of human plasma lipidome using machine learning methods

Genetic architecture of plasma lipidome provides insights into regulation of lipid metabolism and related diseases. We applied an unsupervised machine learning method, PGMRA, to discover phenotype-genotype many-to-many relations between genotype and plasma lipidome (phenotype) in order to identify t...

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Detalles Bibliográficos
Autores principales: Lehtimäki, Miikael, Mishra, Binisha H., Del-Val, Coral, Lyytikäinen, Leo-Pekka, Kähönen, Mika, Cloninger, C. Robert, Raitakari, Olli T., Laaksonen, Reijo, Zwir, Igor, Lehtimäki, Terho, Mishra, Pashupati P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947228/
https://www.ncbi.nlm.nih.gov/pubmed/36813803
http://dx.doi.org/10.1038/s41598-023-30168-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947228/
https://www.ncbi.nlm.nih.gov/pubmed/36813803
http://dx.doi.org/10.1038/s41598-023-30168-z

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