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Myeloid-cell-specific role of Gasdermin D in promoting lung cancer progression in mice

The activities of the NLRP3 and AIM2 inflammasomes and Gasdermin D (GsdmD) are implicated in lung cancer pathophysiology but it’s not clear if their contributions promote or retard lung cancer progression. Using a metastatic Lewis lung carcinoma (LLC) cell model, we show that GsdmD knockout (GsdmD(−...

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Detalles Bibliográficos
Autores principales:	Traughber, C. Alicia, Deshpande, Gauravi M., Neupane, Kalash, Bhandari, Nilam, Khan, Mariam R., McMullen, Megan R., Swaidani, Shadi, Opoku, Emmanuel, Muppala, Santoshi, Smith, Jonathan D., Nagy, Laura E., Gulshan, Kailash
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947301/ https://www.ncbi.nlm.nih.gov/pubmed/36844454 http://dx.doi.org/10.1016/j.isci.2023.106076

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