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Study on sustainable development of pharmaceutical health industry under ecological coordination

Particularly in the post-pandemic period, where public health emergencies offer a greater risk of supply disruptions, the operational hazards of pharmaceutical supply chains are uncertain. One of the main concerns for businesses is how to handle the risk of supply disruption and take the necessary p...

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Autores principales: Fu, Gan, Zhao, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947403/
https://www.ncbi.nlm.nih.gov/pubmed/36844849
http://dx.doi.org/10.3389/fpubh.2023.1117701
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author Fu, Gan
Zhao, Zhao
author_facet Fu, Gan
Zhao, Zhao
author_sort Fu, Gan
collection PubMed
description Particularly in the post-pandemic period, where public health emergencies offer a greater risk of supply disruptions, the operational hazards of pharmaceutical supply chains are uncertain. One of the main concerns for businesses is how to handle the risk of supply disruption and take the necessary precautions to lower the chance of loss. Pharmaceutical raw material suppliers, pharmaceutical manufacturers and medical institutions constitute a complete three-tiered supply chain. On the basis of this, in Materials and methods part, a share contract based on buyback proceeds is created as a result, and a combination contract based on centralized decision-making and decentralized decision-making is employed to maximize the order volume of pharmaceutical supply chain participants. An out-of-stock cost pharmaceutical supply chain model is created, and a related solution is provided and measurable examples. In Results and discussion part, to confirm the accuracy of the model and algorithm, numerical examples are employed. Buyback prices and order volumes were subjected to sensitivity analysis, and discussion is had over how various parameters affect a model's performance. Due to supply disruptions, the study's findings show that there is “double sourcing” between upstream pharmaceutical raw materials and downstream major suppliers, necessitating the establishment of a supply chain with numerous standby suppliers. At the same time, modifying the contract parameters can improve the supply motivation of backup suppliers and guarantee the profitability of downstream medical institutions.
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spelling pubmed-99474032023-02-24 Study on sustainable development of pharmaceutical health industry under ecological coordination Fu, Gan Zhao, Zhao Front Public Health Public Health Particularly in the post-pandemic period, where public health emergencies offer a greater risk of supply disruptions, the operational hazards of pharmaceutical supply chains are uncertain. One of the main concerns for businesses is how to handle the risk of supply disruption and take the necessary precautions to lower the chance of loss. Pharmaceutical raw material suppliers, pharmaceutical manufacturers and medical institutions constitute a complete three-tiered supply chain. On the basis of this, in Materials and methods part, a share contract based on buyback proceeds is created as a result, and a combination contract based on centralized decision-making and decentralized decision-making is employed to maximize the order volume of pharmaceutical supply chain participants. An out-of-stock cost pharmaceutical supply chain model is created, and a related solution is provided and measurable examples. In Results and discussion part, to confirm the accuracy of the model and algorithm, numerical examples are employed. Buyback prices and order volumes were subjected to sensitivity analysis, and discussion is had over how various parameters affect a model's performance. Due to supply disruptions, the study's findings show that there is “double sourcing” between upstream pharmaceutical raw materials and downstream major suppliers, necessitating the establishment of a supply chain with numerous standby suppliers. At the same time, modifying the contract parameters can improve the supply motivation of backup suppliers and guarantee the profitability of downstream medical institutions. Frontiers Media S.A. 2023-02-09 /pmc/articles/PMC9947403/ /pubmed/36844849 http://dx.doi.org/10.3389/fpubh.2023.1117701 Text en Copyright © 2023 Fu and Zhao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Fu, Gan
Zhao, Zhao
Study on sustainable development of pharmaceutical health industry under ecological coordination
title Study on sustainable development of pharmaceutical health industry under ecological coordination
title_full Study on sustainable development of pharmaceutical health industry under ecological coordination
title_fullStr Study on sustainable development of pharmaceutical health industry under ecological coordination
title_full_unstemmed Study on sustainable development of pharmaceutical health industry under ecological coordination
title_short Study on sustainable development of pharmaceutical health industry under ecological coordination
title_sort study on sustainable development of pharmaceutical health industry under ecological coordination
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947403/
https://www.ncbi.nlm.nih.gov/pubmed/36844849
http://dx.doi.org/10.3389/fpubh.2023.1117701
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