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Overexpressed Nup88 stabilized through interaction with Nup62 promotes NF-κB dependent pathways in cancer

Bidirectional nucleo-cytoplasmic transport, regulating several vital cellular processes, is mediated by the Nuclear Pore Complex (NPC) comprising the nucleoporin (Nup) proteins. Nup88, a constituent nucleoporin, is overexpressed in many cancers, and a positive correlation exists between progressive...

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Detalles Bibliográficos
Autores principales: Singh, Usha, Bindra, Divya, Samaiya, Atul, Mishra, Ram Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947638/
https://www.ncbi.nlm.nih.gov/pubmed/36845732
http://dx.doi.org/10.3389/fonc.2023.1095046