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Old age promotes retinal fibrosis in choroidal neovascularization through circulating fibrocytes and profibrotic macrophages

BACKGROUND: Retinal fibrosis affects 40–70% of neovascular age-related macular degeneration patients. This study investigated the effect of ageing on subretinal fibrosis secondary to choroidal neovascularization and the mechanism of action. METHODS: Subretinal fibrosis was induced in young (2.5-mont...

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Detalles Bibliográficos
Autores principales:	Yi, Caijiao, Liu, Jian, Deng, Wen, Luo, Chang, Qi, Jinyan, Chen, Mei, Xu, Heping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947907/ https://www.ncbi.nlm.nih.gov/pubmed/36823538 http://dx.doi.org/10.1186/s12974-023-02731-y

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