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Implicit feedback policies for COVID-19: why “zero-COVID” policies remain elusive

Successful epidemic modeling requires understanding the implicit feedback control strategies used by populations to modulate the spread of contagion. While such strategies can be replicated with intricate modeling assumptions, here we propose a simple model where infection dynamics are described by...

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Detalles Bibliográficos
Autores principales: Jadbabaie, Ali, Sarker, Arnab, Shah, Devavrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947911/
https://www.ncbi.nlm.nih.gov/pubmed/36823214
http://dx.doi.org/10.1038/s41598-023-29542-8
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author Jadbabaie, Ali
Sarker, Arnab
Shah, Devavrat
author_facet Jadbabaie, Ali
Sarker, Arnab
Shah, Devavrat
author_sort Jadbabaie, Ali
collection PubMed
description Successful epidemic modeling requires understanding the implicit feedback control strategies used by populations to modulate the spread of contagion. While such strategies can be replicated with intricate modeling assumptions, here we propose a simple model where infection dynamics are described by a three parameter feedback policy. Rather than model individuals as directly controlling the contact rate which governs the spread of disease, we model them as controlling the contact rate’s derivative, resulting in a dynamic rather than kinematic model. The feedback policy used by populations across the United States which best fits observations is proportional-derivative control, where learned parameters strongly correlate with observed interventions (e.g., vaccination rates and mobility restrictions). However, this results in a non-zero “steady-state” of case counts, implying current mitigation strategies cannot eradicate COVID-19. Hence, we suggest making implicit policies a function of cumulative cases, resulting in proportional-integral-derivative control with higher potential to eliminate COVID-19.
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spelling pubmed-99479112023-02-23 Implicit feedback policies for COVID-19: why “zero-COVID” policies remain elusive Jadbabaie, Ali Sarker, Arnab Shah, Devavrat Sci Rep Article Successful epidemic modeling requires understanding the implicit feedback control strategies used by populations to modulate the spread of contagion. While such strategies can be replicated with intricate modeling assumptions, here we propose a simple model where infection dynamics are described by a three parameter feedback policy. Rather than model individuals as directly controlling the contact rate which governs the spread of disease, we model them as controlling the contact rate’s derivative, resulting in a dynamic rather than kinematic model. The feedback policy used by populations across the United States which best fits observations is proportional-derivative control, where learned parameters strongly correlate with observed interventions (e.g., vaccination rates and mobility restrictions). However, this results in a non-zero “steady-state” of case counts, implying current mitigation strategies cannot eradicate COVID-19. Hence, we suggest making implicit policies a function of cumulative cases, resulting in proportional-integral-derivative control with higher potential to eliminate COVID-19. Nature Publishing Group UK 2023-02-23 /pmc/articles/PMC9947911/ /pubmed/36823214 http://dx.doi.org/10.1038/s41598-023-29542-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Jadbabaie, Ali
Sarker, Arnab
Shah, Devavrat
Implicit feedback policies for COVID-19: why “zero-COVID” policies remain elusive
title Implicit feedback policies for COVID-19: why “zero-COVID” policies remain elusive
title_full Implicit feedback policies for COVID-19: why “zero-COVID” policies remain elusive
title_fullStr Implicit feedback policies for COVID-19: why “zero-COVID” policies remain elusive
title_full_unstemmed Implicit feedback policies for COVID-19: why “zero-COVID” policies remain elusive
title_short Implicit feedback policies for COVID-19: why “zero-COVID” policies remain elusive
title_sort implicit feedback policies for covid-19: why “zero-covid” policies remain elusive
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947911/
https://www.ncbi.nlm.nih.gov/pubmed/36823214
http://dx.doi.org/10.1038/s41598-023-29542-8
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