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Exploration of SARS-CoV-2 Mpro Noncovalent Natural Inhibitors Using Structure-Based Approaches

[Image: see text] With the emergence of antibody-evasive omicron subvariants (BA.2.12.1, BA.4, and BA.5), which can compromise the efficacy of vaccination, it is of utmost importance to widen the finite therapeutic options for COVID-19. Although more than 600 co-crystal complexes of Mpro with inhibi...

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Detalles Bibliográficos
Autores principales: Duong, Cuong Quoc, Nguyen, Phuong Thuy Viet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947982/
https://www.ncbi.nlm.nih.gov/pubmed/36844600
http://dx.doi.org/10.1021/acsomega.2c07259