The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56(bright) NK cells

The crosstalk between NK cells and their surrounding environment is enabled through activating and inhibitory receptors, which tightly control NK cell activity. The co-inhibitory receptor TIGIT decreases NK cell cytotoxicity and is involved in NK cell exhaustion, but has also been associated with li...

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Detalles Bibliográficos
Autores principales: Ziegler, Annerose E., Fittje, Pia, Müller, Luisa M., Ahrenstorf, Annika E., Hagemann, Kerri, Hagen, Sven H., Hess, Leonard U., Niehrs, Annika, Poch, Tobias, Ravichandran, Gevitha, Löbl, Sebastian M., Padoan, Benedetta, Brias, Sébastien, Hennesen, Jana, Richard, Myrtille, Richert, Laura, Peine, Sven, Oldhafer, Karl J., Fischer, Lutz, Schramm, Christoph, Martrus, Glòria, Bunders, Madeleine J., Altfeld, Marcus, Lunemann, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948018/
https://www.ncbi.nlm.nih.gov/pubmed/36845105
http://dx.doi.org/10.3389/fimmu.2023.1117320

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