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Salvage Nipple-sparing Mastectomy for Patients with Breast Cancer Recurrence: A Case Series of Brazilian Patients

Objective  Few studies analyzed the safety of salvage nipple-sparing mastectomy (NSM) for local relapse treatment. We evaluated the outcomes of patients with indications for mastectomy who chose to undergo NSM for ipsilateral breast tumor recurrence (IBTR). Methods  Between January 2001 and December...

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Autores principales: Frasson, Antônio Luiz, Lichtenfels, Martina, Barbosa, Fernanda, Souza, Alessandra Borba Anton de, Falcone, Ana Beatriz, Miranda, Isabela, Vollbrecht, Betina, Malhone, Carolina, Tariki, José Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948044/
https://www.ncbi.nlm.nih.gov/pubmed/35211933
http://dx.doi.org/10.1055/s-0042-1743098
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author Frasson, Antônio Luiz
Lichtenfels, Martina
Barbosa, Fernanda
Souza, Alessandra Borba Anton de
Falcone, Ana Beatriz
Miranda, Isabela
Vollbrecht, Betina
Malhone, Carolina
Tariki, José Yoshikazu
author_facet Frasson, Antônio Luiz
Lichtenfels, Martina
Barbosa, Fernanda
Souza, Alessandra Borba Anton de
Falcone, Ana Beatriz
Miranda, Isabela
Vollbrecht, Betina
Malhone, Carolina
Tariki, José Yoshikazu
author_sort Frasson, Antônio Luiz
collection PubMed
description Objective  Few studies analyzed the safety of salvage nipple-sparing mastectomy (NSM) for local relapse treatment. We evaluated the outcomes of patients with indications for mastectomy who chose to undergo NSM for ipsilateral breast tumor recurrence (IBTR). Methods  Between January 2001 and December 2018, we evaluated 24 women who underwent NSM for local relapse after conservative surgery. Results  The patients were followed up for a mean time of 132 months since the first surgery. After the NSM, 5 (20.8%) patients were diagnosed with local recurrence and only 1 (4.2%) patient died. The patients presented 4.8% (2) of partial and 2.4% (1) of total nipple necrosis. Conclusion  In this long-term follow-up since the first surgery, we observed low rates of complication and good survival, although associated with high local recurrence in patients diagnosed with IBTR undergoing NSM as salvage surgery. We demonstrated that NSM may be considered after IBTR for patients who did not want to undergo total mastectomy.
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spelling pubmed-99480442023-07-27 Salvage Nipple-sparing Mastectomy for Patients with Breast Cancer Recurrence: A Case Series of Brazilian Patients Frasson, Antônio Luiz Lichtenfels, Martina Barbosa, Fernanda Souza, Alessandra Borba Anton de Falcone, Ana Beatriz Miranda, Isabela Vollbrecht, Betina Malhone, Carolina Tariki, José Yoshikazu Rev Bras Ginecol Obstet Objective  Few studies analyzed the safety of salvage nipple-sparing mastectomy (NSM) for local relapse treatment. We evaluated the outcomes of patients with indications for mastectomy who chose to undergo NSM for ipsilateral breast tumor recurrence (IBTR). Methods  Between January 2001 and December 2018, we evaluated 24 women who underwent NSM for local relapse after conservative surgery. Results  The patients were followed up for a mean time of 132 months since the first surgery. After the NSM, 5 (20.8%) patients were diagnosed with local recurrence and only 1 (4.2%) patient died. The patients presented 4.8% (2) of partial and 2.4% (1) of total nipple necrosis. Conclusion  In this long-term follow-up since the first surgery, we observed low rates of complication and good survival, although associated with high local recurrence in patients diagnosed with IBTR undergoing NSM as salvage surgery. We demonstrated that NSM may be considered after IBTR for patients who did not want to undergo total mastectomy. Thieme Revinter Publicações Ltda. 2022-02-24 /pmc/articles/PMC9948044/ /pubmed/35211933 http://dx.doi.org/10.1055/s-0042-1743098 Text en Federação Brasileira de Ginecologia e Obstetrícia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Frasson, Antônio Luiz
Lichtenfels, Martina
Barbosa, Fernanda
Souza, Alessandra Borba Anton de
Falcone, Ana Beatriz
Miranda, Isabela
Vollbrecht, Betina
Malhone, Carolina
Tariki, José Yoshikazu
Salvage Nipple-sparing Mastectomy for Patients with Breast Cancer Recurrence: A Case Series of Brazilian Patients
title Salvage Nipple-sparing Mastectomy for Patients with Breast Cancer Recurrence: A Case Series of Brazilian Patients
title_full Salvage Nipple-sparing Mastectomy for Patients with Breast Cancer Recurrence: A Case Series of Brazilian Patients
title_fullStr Salvage Nipple-sparing Mastectomy for Patients with Breast Cancer Recurrence: A Case Series of Brazilian Patients
title_full_unstemmed Salvage Nipple-sparing Mastectomy for Patients with Breast Cancer Recurrence: A Case Series of Brazilian Patients
title_short Salvage Nipple-sparing Mastectomy for Patients with Breast Cancer Recurrence: A Case Series of Brazilian Patients
title_sort salvage nipple-sparing mastectomy for patients with breast cancer recurrence: a case series of brazilian patients
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948044/
https://www.ncbi.nlm.nih.gov/pubmed/35211933
http://dx.doi.org/10.1055/s-0042-1743098
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