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MassChemSite for In-Depth Forced Degradation Analysis of PARP Inhibitors Olaparib, Rucaparib, and Niraparib

[Image: see text] Drugs must satisfy several protocols and tests before being approved for the market. Among them, forced degradation studies aim to evaluate drug stability under stressful conditions in order to predict the formation of harmful degradation products (DPs). Recent advances in LC–MS in...

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Detalles Bibliográficos
Autores principales: Bonciarelli, Stefano, Desantis, Jenny, Cerquiglini, Simone, Goracci, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948214/
https://www.ncbi.nlm.nih.gov/pubmed/36844573
http://dx.doi.org/10.1021/acsomega.2c07815