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TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1

BACKGROUND: Prostate cancer (PCa) is a common malignant tumor of the genitourinary system. Clinical intervention in advanced PCa remains challenging. Tropomyosins 2 (TPM2) are actin-binding proteins and have been found as a biomarker candidate for certain cancers. However, no studies have explored t...

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Detalles Bibliográficos
Autores principales: Wu, Zonglong, Ge, Liyuan, Ma, Lulin, Lu, Min, Song, Yimeng, Deng, Shaohui, Duan, Peichen, Du, Tan, Wu, Yaqian, Zhang, Zhanyi, Zhang, Shudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948342/
https://www.ncbi.nlm.nih.gov/pubmed/36823643
http://dx.doi.org/10.1186/s13578-023-00993-w