Estrogen downregulates CD73/adenosine axis hyperactivity via adaptive modulation PI3K/Akt signaling to prevent myocarditis and arrhythmias during chronic catecholamines stress

BACKGROUND: During myocardial damage, the sex hormone estrogen and CD73, the main enzyme that converts AMP into adenosine, are cardioprotective molecules. However, it is unclear how these two molecules work together to provide cardioprotection. The current study aimed to elucidate the interaction be...

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Detalles Bibliográficos
Autores principales: Ndzie Noah, Marie Louise, Adzika, Gabriel Komla, Mprah, Richard, Adekunle, Adebayo Oluwafemi, Koda, Stephane, Adu-Amankwaah, Joseph, Xu, Yaxin, Kanwore, Kouminin, Wowui, Prosperl Ivette, Sun, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948346/
https://www.ncbi.nlm.nih.gov/pubmed/36823590
http://dx.doi.org/10.1186/s12964-023-01052-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948346/
https://www.ncbi.nlm.nih.gov/pubmed/36823590
http://dx.doi.org/10.1186/s12964-023-01052-0

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