A 3D human co-culture to model neuron-astrocyte interactions in tauopathies

BACKGROUND: Intraneuronal tau aggregation is the major pathological hallmark of neurodegenerative tauopathies. It is now generally acknowledged that tau aggregation also affects astrocytes in a cell non-autonomous manner. However, mechanisms involved are unclear, partly because of the lack of models...

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Autores principales: Batenburg, Kevin L., Sestito, Claudia, Cornelissen-Steijger, Paulien, van Weering, Jan R. T., Price, Leo S., Heine, Vivi M., Scheper, Wiep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948470/
https://www.ncbi.nlm.nih.gov/pubmed/36814189
http://dx.doi.org/10.1186/s12575-023-00194-2

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