Low-intensity pulsed ultrasound triggers a beneficial neuromodulation in dementia mice with chronic cerebral hypoperfusion via activation of hippocampal Fndc5/irisin signaling

BACKGROUND: Exercise-related signaling Fndc5/irisin expresses in brain and acts as a crucial regulator of cognitive function, but its detailed roles in vascular dementia (VaD) are still unclear. Low intensity pulsed ultrasound (LIPUS), a novel brain stimulation approach, has been suggested as a prom...

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Detalles Bibliográficos
Autores principales: Song, Degang, Chen, Xiaomin, Zhou, Na, Yuan, Yi, Geng, Shuo, Zhang, Cong, Zhao, Zhe, Wang, Xingran, Bao, Xinran, Lan, Xifa, Zhang, Xiangjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948478/
https://www.ncbi.nlm.nih.gov/pubmed/36823656
http://dx.doi.org/10.1186/s12967-022-03824-7

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