Similar voltage-sensor movement in spHCN channels can cause closing, opening, or inactivation

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels contribute to the rhythmic firing of pacemaker neurons and cardiomyocytes. Mutations in HCN channels are associated with cardiac arrhythmia and epilepsy. HCN channels belong to the superfamily of voltage-gated K(+) channels, most of...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoan, Cunningham, Kevin P., Ramentol, Rosamary, Perez, Marta E., Larsson, H. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948645/
https://www.ncbi.nlm.nih.gov/pubmed/36752823
http://dx.doi.org/10.1085/jgp.202213170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948645/
https://www.ncbi.nlm.nih.gov/pubmed/36752823
http://dx.doi.org/10.1085/jgp.202213170

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