Inhibition of Ribosome Assembly and Ribosome Translation Has Distinctly Different Effects on Abundance and Paralogue Composition of Ribosomal Protein mRNAs in Saccharomyces cerevisiae

Many mutations in genes for ribosomal proteins (r-proteins) and assembly factors cause cell stress and altered cell fate, resulting in congenital diseases collectively called ribosomopathies. Even though all such mutations depress the cell’s protein synthesis capacity, they generate many different p...

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Detalles Bibliográficos
Autores principales: Shamsuzzaman, Md, Rahman, Nusrat, Gregory, Brian, Bommakanti, Ananth, Zengel, Janice M., Bruno, Vincent M., Lindahl, Lasse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948716/
https://www.ncbi.nlm.nih.gov/pubmed/36651729
http://dx.doi.org/10.1128/msystems.01098-22

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