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Intranasal multivalent adenoviral-vectored vaccine protects against replicating and dormant M.tb in conventional and humanized mice

Viral-vectored vaccines are highly amenable for respiratory mucosal delivery as a means of inducing much-needed mucosal immunity at the point of pathogen entry. Unfortunately, current monovalent viral-vectored tuberculosis (TB) vaccine candidates have failed to demonstrate satisfactory clinical prot...

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Detalles Bibliográficos
Autores principales:	Afkhami, Sam, D’Agostino, Michael R., Vaseghi-Shanjani, Maryam, Lepard, Madeleine, Yang, Jack X., Lai, Rocky, Choi, Margaret Wa Yan, Chacon, Alexis, Zganiacz, Anna, Franken, Kees L. M. C., Ertl, Hildegund C., Ottenhoff, Tom H. M., Jeyanathan, Mangalakumari, Gillgrass, Amy, Xing, Zhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948798/ https://www.ncbi.nlm.nih.gov/pubmed/36823425 http://dx.doi.org/10.1038/s41541-023-00623-z

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