Cargando…
Impact of an overdose reversal program in the context of a safe consumption site in Northern Mexico
BACKGROUND: Drug overdoses are prevalent in low- and middle-income countries but are scarcely reported in the literature. We report on an opioid overdose reversal and naloxone distribution program that was instituted at the first safe consumption site in Latin America. METHODS: A cross-sectional ana...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948854/ https://www.ncbi.nlm.nih.gov/pubmed/36845896 http://dx.doi.org/10.1016/j.dadr.2021.100021 |
_version_ | 1784892867751182336 |
---|---|
author | Goodman-Meza, David Slim, Said Angulo, Lourdes Gonzalez-Nieto, Pablo Cambou, Mary C. Loera, Alejandra Shoptaw, Steve Arredondo, Jaime |
author_facet | Goodman-Meza, David Slim, Said Angulo, Lourdes Gonzalez-Nieto, Pablo Cambou, Mary C. Loera, Alejandra Shoptaw, Steve Arredondo, Jaime |
author_sort | Goodman-Meza, David |
collection | PubMed |
description | BACKGROUND: Drug overdoses are prevalent in low- and middle-income countries but are scarcely reported in the literature. We report on an opioid overdose reversal and naloxone distribution program that was instituted at the first safe consumption site in Latin America. METHODS: A cross-sectional analysis of witnessed drug overdoses and naloxone distribution between 1 June 2019 and 31 May 2021 in Mexicali, Mexico. Case report forms were entered in an electronic database. Trends in overdose and naloxone distribution were described. Comparisons were made before and after the COVID-19 pandemic was declared in the city. Maps were created to represent the geographic distribution of overdose in the city. RESULTS: During the study period 1,534 doses of naloxone were distributed throughout the community. In addition, there were 464 overdoses reported during this period, of which 4 were fatal. There was a 30% increase in reported overdoses from the period before the COVID-19 pandemic to the period after the pandemic was declared (p = 0.03). Most common substance reported included heroin (93%), sedatives (21%), methamphetamine (16%) and fentanyl (14%). Naloxone was given in 96% of cases (median 1 dose, IQR 1–2 doses) and emergency services were called in 20% of cases. CONCLUSIONS: An opioid overdose reversal program in Mexicali, Mexico was able to distribute naloxone and register drug overdoses between 2019 and 2021 as a harm reduction strategy. This adds to the growing body of literature on the impact of community-based programs on preventing fatal overdoses and the potential for implementation in low-resource settings. |
format | Online Article Text |
id | pubmed-9948854 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-99488542023-02-23 Impact of an overdose reversal program in the context of a safe consumption site in Northern Mexico Goodman-Meza, David Slim, Said Angulo, Lourdes Gonzalez-Nieto, Pablo Cambou, Mary C. Loera, Alejandra Shoptaw, Steve Arredondo, Jaime Drug Alcohol Depend Rep Short Communication BACKGROUND: Drug overdoses are prevalent in low- and middle-income countries but are scarcely reported in the literature. We report on an opioid overdose reversal and naloxone distribution program that was instituted at the first safe consumption site in Latin America. METHODS: A cross-sectional analysis of witnessed drug overdoses and naloxone distribution between 1 June 2019 and 31 May 2021 in Mexicali, Mexico. Case report forms were entered in an electronic database. Trends in overdose and naloxone distribution were described. Comparisons were made before and after the COVID-19 pandemic was declared in the city. Maps were created to represent the geographic distribution of overdose in the city. RESULTS: During the study period 1,534 doses of naloxone were distributed throughout the community. In addition, there were 464 overdoses reported during this period, of which 4 were fatal. There was a 30% increase in reported overdoses from the period before the COVID-19 pandemic to the period after the pandemic was declared (p = 0.03). Most common substance reported included heroin (93%), sedatives (21%), methamphetamine (16%) and fentanyl (14%). Naloxone was given in 96% of cases (median 1 dose, IQR 1–2 doses) and emergency services were called in 20% of cases. CONCLUSIONS: An opioid overdose reversal program in Mexicali, Mexico was able to distribute naloxone and register drug overdoses between 2019 and 2021 as a harm reduction strategy. This adds to the growing body of literature on the impact of community-based programs on preventing fatal overdoses and the potential for implementation in low-resource settings. Elsevier 2021-12-23 /pmc/articles/PMC9948854/ /pubmed/36845896 http://dx.doi.org/10.1016/j.dadr.2021.100021 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Short Communication Goodman-Meza, David Slim, Said Angulo, Lourdes Gonzalez-Nieto, Pablo Cambou, Mary C. Loera, Alejandra Shoptaw, Steve Arredondo, Jaime Impact of an overdose reversal program in the context of a safe consumption site in Northern Mexico |
title | Impact of an overdose reversal program in the context of a safe consumption site in Northern Mexico |
title_full | Impact of an overdose reversal program in the context of a safe consumption site in Northern Mexico |
title_fullStr | Impact of an overdose reversal program in the context of a safe consumption site in Northern Mexico |
title_full_unstemmed | Impact of an overdose reversal program in the context of a safe consumption site in Northern Mexico |
title_short | Impact of an overdose reversal program in the context of a safe consumption site in Northern Mexico |
title_sort | impact of an overdose reversal program in the context of a safe consumption site in northern mexico |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948854/ https://www.ncbi.nlm.nih.gov/pubmed/36845896 http://dx.doi.org/10.1016/j.dadr.2021.100021 |
work_keys_str_mv | AT goodmanmezadavid impactofanoverdosereversalprograminthecontextofasafeconsumptionsiteinnorthernmexico AT slimsaid impactofanoverdosereversalprograminthecontextofasafeconsumptionsiteinnorthernmexico AT angulolourdes impactofanoverdosereversalprograminthecontextofasafeconsumptionsiteinnorthernmexico AT gonzaleznietopablo impactofanoverdosereversalprograminthecontextofasafeconsumptionsiteinnorthernmexico AT camboumaryc impactofanoverdosereversalprograminthecontextofasafeconsumptionsiteinnorthernmexico AT loeraalejandra impactofanoverdosereversalprograminthecontextofasafeconsumptionsiteinnorthernmexico AT shoptawsteve impactofanoverdosereversalprograminthecontextofasafeconsumptionsiteinnorthernmexico AT arredondojaime impactofanoverdosereversalprograminthecontextofasafeconsumptionsiteinnorthernmexico |