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Transmembrane protein CD69 acts as an S1PR1 agonist

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The activation of Sphingosine-1-phosphate receptor 1 (S1PR1) by S1P promotes lymphocyte egress from lymphoid organs, a process critical for immune surveillance and T cell effector activity (1–4). Multiple drugs that inhibit S1PR1 function are in use clinically for the treatment of autoimmune disease...

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Detalles Bibliográficos
Autores principales:	Chen, Hongwen, Qin, Yu, Chou, Marissa, Cyster, Jason G., Li, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949048/ https://www.ncbi.nlm.nih.gov/pubmed/36824756 http://dx.doi.org/10.1101/2023.02.13.528406

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