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Transmembrane protein CD69 acts as an S1PR1 agonist
The activation of Sphingosine-1-phosphate receptor 1 (S1PR1) by S1P promotes lymphocyte egress from lymphoid organs, a process critical for immune surveillance and T cell effector activity (1–4). Multiple drugs that inhibit S1PR1 function are in use clinically for the treatment of autoimmune disease...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949048/ https://www.ncbi.nlm.nih.gov/pubmed/36824756 http://dx.doi.org/10.1101/2023.02.13.528406 |
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