Mixed IgG Fc immune complexes exhibit blended binding profiles and refine FcR affinity estimates

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Immunoglobulin (Ig)G antibodies coordinate immune effector responses by selectively binding to target antigens and then interacting with various effector cells via the Fcγ receptors. The Fc domain of IgG can promote or inhibit distinct effector responses across several different immune cell types th...

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Detalles Bibliográficos
Autores principales: Cyrillus Tan, Zhixin, Lux, Anja, Biburger, Markus, Varghese, Prabha, Lees, Stephen, Nimmerjahn, Falk, Meyer, Aaron S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949097/
https://www.ncbi.nlm.nih.gov/pubmed/36824734
http://dx.doi.org/10.1101/2023.02.15.528730

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