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LPD-3 as a megaprotein brake for aging and insulin-mTOR signaling in C. elegans

Insulin-mTOR signaling drives anabolic growth during organismal development, while its late-life dysregulation may detrimentally contribute to aging and limit lifespans. Age-related regulatory mechanisms and functional consequences of insulin-mTOR remain incompletely understood. Here we identify LPD...

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Detalles Bibliográficos
Autores principales:	Pandey, Taruna, Wang, Bingying, Wang, Changnan, Zu, Jenny, Deng, Huichao, Shen, Kang, do Vale, Goncalo Dias, McDonald, Jeffrey G., Ma, Dengke K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949100/ https://www.ncbi.nlm.nih.gov/pubmed/36824874 http://dx.doi.org/10.1101/2023.02.14.528431

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