The Essential Role of O-GlcNAcylation in Hepatic Differentiation

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BACKGROUND & AIMS. O-GlcNAcylation is a post-translational modification catalyzed by the enzyme O-GlcNAc transferase (OGT), which transfers a single N-acetylglucosamine sugar from UDP-GlcNAc to the protein on serine and threonine residues on proteins. Another enzyme, O-GlcNAcase (OGA), removes t...

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Detalles Bibliográficos
Autores principales: Robarts, Dakota R., Kotulkar, Manasi, Paine-Cabrera, Diego, Venneman, Kaitlyn K., Hanover, John A., Zachara, Natasha E., Slawson, Chad, Apte, Udayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949138/
https://www.ncbi.nlm.nih.gov/pubmed/36824917
http://dx.doi.org/10.1101/2023.02.16.528884
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